Medical edema protection--clinical benefit in patients with chronic deep vein incompetence. A placebo controlled double blind study.
Identifieur interne : 00D105 ( Main/Exploration ); précédent : 00D104; suivant : 00D106Medical edema protection--clinical benefit in patients with chronic deep vein incompetence. A placebo controlled double blind study.
Auteurs : C. Diehm ; D. Vollbrecht ; K. Amendt ; H U CombergSource :
- VASA. Zeitschrift fur Gefasskrankheiten [ 0301-1526 ] ; 1992.
Descripteurs français
- KwdFr :
- MESH :
- administration et posologie : Aescine, Extraits tissulaires.
- Administration par voie orale, Adulte, Adulte d'âge moyen, Femelle, Humains, Insuffisance veineuse, Lymphoedème, Mâle, Méthode en double aveugle, Sujet âgé, Épreuve d'effort.
English descriptors
- KwdEn :
- MESH :
- chemical , administration & dosage : Escin, Tissue Extracts.
- complications : Venous Insufficiency.
- drug effects : Exercise Test.
- therapy : Lymphedema.
- Administration, Oral, Adult, Aged, Double-Blind Method, Female, Humans, Male, Middle Aged.
Abstract
In a randomized placebo controlled parallel double blind study on 40 patients suffering from venous edema in chronic deep vein incompetence, the edema-reducing effect of horse chestnut seed extract vs. placebo, being the main test variable, was demonstrated by hydroplethysmography to be statistically significant. In addition, measurements of leg volume under aggravated conditions (edema provocation) were conducted, which yielded the same results. Additional measurements of leg circumference tendentially confirm the demonstrated clinical efficacy of verum, as is true for phlebody-namometric measurements (pressure at rest, minimum pressure, replenishment time) as well. By measuring the leg volume before and after edema provocation, it could be shown that the clinical benefit for the patient is present in all everyday situations (in movement as well as on sitting or standing). Treatment with an edema protective agent of the horse chestnut seed extract type is thus a useful adjunct to compression therapy. The tested preparation were well tolerated.
PubMed: 1621440
Affiliations:
Links toward previous steps (curation, corpus...)
- to stream PubMed, to step Corpus: 005995
- to stream PubMed, to step Curation: 005995
- to stream PubMed, to step Checkpoint: 005995
- to stream Ncbi, to step Merge: 001F88
- to stream Ncbi, to step Curation: 001F88
- to stream Ncbi, to step Checkpoint: 001F88
- to stream Main, to step Merge: 00DB76
- to stream Main, to step Curation: 00D105
Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Medical edema protection--clinical benefit in patients with chronic deep vein incompetence. A placebo controlled double blind study.</title><author><name sortKey="Diehm, C" sort="Diehm, C" uniqKey="Diehm C" first="C" last="Diehm">C. Diehm</name><affiliation><nlm:affiliation>Dept. of Internal Medicine III, University of Heidelberg.</nlm:affiliation><wicri:noCountry code="subField">University of Heidelberg</wicri:noCountry></affiliation></author><author><name sortKey="Vollbrecht, D" sort="Vollbrecht, D" uniqKey="Vollbrecht D" first="D" last="Vollbrecht">D. Vollbrecht</name></author><author><name sortKey="Amendt, K" sort="Amendt, K" uniqKey="Amendt K" first="K" last="Amendt">K. Amendt</name></author><author><name sortKey="Comberg, H U" sort="Comberg, H U" uniqKey="Comberg H" first="H U" last="Comberg">H U Comberg</name></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="1992">1992</date><idno type="RBID">pubmed:1621440</idno><idno type="pmid">1621440</idno><idno type="wicri:Area/PubMed/Corpus">005995</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">005995</idno><idno type="wicri:Area/PubMed/Curation">005995</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">005995</idno><idno type="wicri:Area/PubMed/Checkpoint">005995</idno><idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">005995</idno><idno type="wicri:Area/Ncbi/Merge">001F88</idno><idno type="wicri:Area/Ncbi/Curation">001F88</idno><idno type="wicri:Area/Ncbi/Checkpoint">001F88</idno><idno type="wicri:doubleKey">0301-1526:1992:Diehm C:medical:edema:protection</idno><idno type="wicri:Area/Main/Merge">00DB76</idno><idno type="wicri:Area/Main/Curation">00D105</idno><idno type="wicri:Area/Main/Exploration">00D105</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Medical edema protection--clinical benefit in patients with chronic deep vein incompetence. A placebo controlled double blind study.</title><author><name sortKey="Diehm, C" sort="Diehm, C" uniqKey="Diehm C" first="C" last="Diehm">C. Diehm</name><affiliation><nlm:affiliation>Dept. of Internal Medicine III, University of Heidelberg.</nlm:affiliation><wicri:noCountry code="subField">University of Heidelberg</wicri:noCountry></affiliation></author><author><name sortKey="Vollbrecht, D" sort="Vollbrecht, D" uniqKey="Vollbrecht D" first="D" last="Vollbrecht">D. Vollbrecht</name></author><author><name sortKey="Amendt, K" sort="Amendt, K" uniqKey="Amendt K" first="K" last="Amendt">K. Amendt</name></author><author><name sortKey="Comberg, H U" sort="Comberg, H U" uniqKey="Comberg H" first="H U" last="Comberg">H U Comberg</name></author></analytic><series><title level="j">VASA. Zeitschrift fur Gefasskrankheiten</title><idno type="ISSN">0301-1526</idno><imprint><date when="1992" type="published">1992</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Administration, Oral</term><term>Adult</term><term>Aged</term><term>Double-Blind Method</term><term>Escin (administration & dosage)</term><term>Exercise Test (drug effects)</term><term>Female</term><term>Humans</term><term>Lymphedema (therapy)</term><term>Male</term><term>Middle Aged</term><term>Tissue Extracts (administration & dosage)</term><term>Venous Insufficiency (complications)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Administration par voie orale</term><term>Adulte</term><term>Adulte d'âge moyen</term><term>Aescine (administration et posologie)</term><term>Extraits tissulaires (administration et posologie)</term><term>Femelle</term><term>Humains</term><term>Insuffisance veineuse ()</term><term>Lymphoedème ()</term><term>Mâle</term><term>Méthode en double aveugle</term><term>Sujet âgé</term><term>Épreuve d'effort ()</term></keywords><keywords scheme="MESH" type="chemical" qualifier="administration & dosage" xml:lang="en"><term>Escin</term><term>Tissue Extracts</term></keywords><keywords scheme="MESH" qualifier="administration et posologie" xml:lang="fr"><term>Aescine</term><term>Extraits tissulaires</term></keywords><keywords scheme="MESH" qualifier="complications" xml:lang="en"><term>Venous Insufficiency</term></keywords><keywords scheme="MESH" qualifier="drug effects" xml:lang="en"><term>Exercise Test</term></keywords><keywords scheme="MESH" qualifier="therapy" xml:lang="en"><term>Lymphedema</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Administration, Oral</term><term>Adult</term><term>Aged</term><term>Double-Blind Method</term><term>Female</term><term>Humans</term><term>Male</term><term>Middle Aged</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Administration par voie orale</term><term>Adulte</term><term>Adulte d'âge moyen</term><term>Femelle</term><term>Humains</term><term>Insuffisance veineuse</term><term>Lymphoedème</term><term>Mâle</term><term>Méthode en double aveugle</term><term>Sujet âgé</term><term>Épreuve d'effort</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">In a randomized placebo controlled parallel double blind study on 40 patients suffering from venous edema in chronic deep vein incompetence, the edema-reducing effect of horse chestnut seed extract vs. placebo, being the main test variable, was demonstrated by hydroplethysmography to be statistically significant. In addition, measurements of leg volume under aggravated conditions (edema provocation) were conducted, which yielded the same results. Additional measurements of leg circumference tendentially confirm the demonstrated clinical efficacy of verum, as is true for phlebody-namometric measurements (pressure at rest, minimum pressure, replenishment time) as well. By measuring the leg volume before and after edema provocation, it could be shown that the clinical benefit for the patient is present in all everyday situations (in movement as well as on sitting or standing). Treatment with an edema protective agent of the horse chestnut seed extract type is thus a useful adjunct to compression therapy. The tested preparation were well tolerated.</div></front></TEI><affiliations><list></list><tree><noCountry><name sortKey="Amendt, K" sort="Amendt, K" uniqKey="Amendt K" first="K" last="Amendt">K. Amendt</name><name sortKey="Comberg, H U" sort="Comberg, H U" uniqKey="Comberg H" first="H U" last="Comberg">H U Comberg</name><name sortKey="Diehm, C" sort="Diehm, C" uniqKey="Diehm C" first="C" last="Diehm">C. Diehm</name><name sortKey="Vollbrecht, D" sort="Vollbrecht, D" uniqKey="Vollbrecht D" first="D" last="Vollbrecht">D. Vollbrecht</name></noCountry></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Sante/explor/LymphedemaV1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 00D105 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 00D105 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Sante
|area= LymphedemaV1
|flux= Main
|étape= Exploration
|type= RBID
|clé= pubmed:1621440
|texte= Medical edema protection--clinical benefit in patients with chronic deep vein incompetence. A placebo controlled double blind study.
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i -Sk "pubmed:1621440" \
| HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd \
| NlmPubMed2Wicri -a LymphedemaV1
| This area was generated with Dilib version V0.6.31. |  |